ea0092op-02-05 | Oral Session 2: Thyroid hormone action in the brain | ETA2023
Rotter Jonas
, Biebermann Heike
, Bechmann Ingo
Adequate thyroid hormone levels are crucial for cell homeostasis in the adult human brain. To supply neuronal and glial cells, thyroid hormone (TH) transporters such as the monocarboxylate transporter 8 (MCT8) are required. While implications in TH levels in the human brain seem to play a role in neurodegenerative diseases such as Alzheimers disease (AD), altered expression of TH transporters has not been described yet. Our study therefore aimed to evaluate MCT8 expressi...